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15 search results for: antibiotics

1

When a Popular Class of Antibiotics Turns Toxic

Commonly prescribed drugs called fluoroquinolones, the fourth-most used class of antibiotics in the US, have been shown to cause rare, disabling side effects. Patients have experienced pain in tendons, joints and muscles, neurological and psychological difficulties. Researchers now have a few theories why such symptoms may occur.

3

New Synthesis Technique Leads to Over 300 Candidate Antibiotics

The combination of drug misuse, reductions in antimicrobial research by the pharmaceutical industry, and the rapid evolution capabilities of microorganisms has resulted in pathogenic bacteria with stronger and stronger drug resistance. This is an issue that some fear if not handled correctly, could lead to the evolution of a “superbug” that is resistant to everything […]

4

Bugs on Drugs: Devastating Effects of Pharmaceutical Pollution

An international team of researchers detected a vast sixty-nine pharmaceutical compounds in stream insects. When these insects emerge as flying adults, they can pass these drugs further to spiders, fish, birds, bats, and other streamside foragers. This way, drug pollution moves up food webs and in some cases exposes even top predators to therapeutically-effective doses.

5

Developing Modern Medicines By Simulating The Human Immune System

Rather than relying on serendipity to discover novel therapeutics, today we can work intelligently to identify antibodies that target exactly what we desire. Our immune system has been refined through millions of years of evolution, and our ability to harvest its capabilities now allows us to develop intelligently designed antibody-based medicines. This new generation of […]

7

Breakthroughs in 2017 That Caught Our Attention

The pace of progress in science in recent years is remarkable. Mostly, due to the fact that processes which took weeks to complete can now be done in minutes. Therefore, the past year was definitely fruitful for science. Scientists cooperated and even some global scale projects saw the light of day. Splice would like to review the […]

8

Single Base Editing Is Now Possible With CRISPR

Researchers have reached a new milestone in CRISPR technology by building an enzyme that can directly transform a DNA base pair from an A-T to a G-C. It will allow for more precise edits than ever before, opening doors for “DNA surgeries” and correction of mutations that cause human diseases.

9

New Cpf1 Molecular Scissors to Take Genomic Editing to the Next Level

CRISPR (Clustered Regularly Interspaced Palindromic Repeats) gene editing technology allows permanent modification of genes within organisms. It is considered a breakthrough in biotechnology ever since its discovery.  Researchers from the University of Copenhagen (Denmark), led by Spanish researcher Guillermo Montoya, now went one step further. They discovered how Cpf1, a new type of molecular scissors, unzip […]