A group of US researchers proposed a cutting edge alternative for eliminating resilient bacteria in the form of a “CRISPR pill”. The drug can specifically target harmful bugs using a combination of bacteria-seeking viruses and a cocktail of probiotics, making it more potent than most antibiotics.
The combination of drug misuse, reductions in antimicrobial research by the pharmaceutical industry, and the rapid evolution capabilities of microorganisms has resulted in pathogenic bacteria with stronger and stronger drug resistance. This is an issue that some fear if not handled correctly, could lead to the evolution of a “superbug” that is resistant to everything in our arsenal.
CRISPR (Clustered Regularly Interspaced Palindromic Repeats) gene editing technology allows permanent modification of genes within organisms. It is considered a breakthrough in biotechnology ever since its discovery. Researchers from the University of Copenhagen (Denmark), led by Spanish researcher Guillermo Montoya, now went one step further. They discovered how Cpf1, a new type of molecular scissors, unzip and cleave DNA.
Researchers from the University of Birmingham discovered an unsettling link between a major mechanism of antibiotic resistance in bacteria and triclosan, a disinfectant commonly found in household cleaning products.
Canadian researchers discovered that components of maple syrup may boost the antimicrobial effects of antibiotics by as much as 90% when used in combination. This synergy could provide an effective solution for the alarming threat of multi-drug resistant bacteria.
Scientists from Harvard Medical School and Technion-Israel Institute of Technology have ingeniously visualized the Escherichia coli evolution through ever increasing amounts of antibiotics. Inspired by a Hollywood movie billboard, the team constructed the so called Microbial Evolution and Growth Arena i.e. MEGA plate to be able to monitor bacteria’s movement, survival and resistance.
Scientists are making discoveries that change the way we live. Have you ever asked yourself about the revolutionary discoveries that have made a huge impact on our scientific way of thinking and our everyday life?
Recent drug discoveries promise new treatments and cures for many diseases. However, getting a drug to work, not only in experiments with cells in the lab, but also in the human body, is difficult. One challenge? Getting past the body’s line of defense, the immune system, which fights foreign invaders that make it into the body.
There is a lot of bad publicity around genetic engineering, especially when it comes to the genetic modification of plants and animals. Most opponents of genetic engineering claim that inserting foreign genes into other organism’s genome is unnatural and dangerous.