Researchers at Harvard University developed an effective personalized cancer vaccine that seems to have prevented early tumour relapse in 12 skin cancer patients. The vaccine targeted 20 tumour-specific proteins unique to each of the patients enrolled, keeping all free of cancer over 2 years after the trial.
A new breast cancer drug combination significantly shrunk and eliminated tumours in 28% of women tested in just 11 days. The novel treatment involves a combination of pre-chemotherapy drugs lapatinib and trastuzumab that target HER2-positive tumours.
British scientists developed a revolutionary method for screening cancer using breath-analyzing technology. In a preliminary study involving more than 300 patients the instrument was capable of diagnosing those with esophageal and stomach cancer with 85% accuracy.
Researchers at the University of Michigan developed an impressive new way of delivering customized therapeutic cancer vaccines using antigen-carrying nanodiscs. The treatment showed excellent success in mice, drastically decreasing the occurrence of colon and melanoma tumours.
Resarchers discovered a direct link between high-fat diets and the onset of metastasis in human cancers. Their findings raise concern considering today´s unhealthy lifestyles, but may in fact lead to significant improvements in cancer therapy and prevention.
While bacterial infections usually are a bad thing, they can now be used as a therapy to treat medical conditions, for instance, cancer.
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. There are some forms of cancer which can be cured relatively well with known and established drugs and surgery. However, not all forms of cancer response to these approaches.
This is no novel idea, but after 17 years of a spirited debated, pharmaceutical companies are finally taking note. It was Dr. Mary Hendrix and her team out of the University of Iowa Cancer center in Iowa City who first reported in 1999 that human melanoma tumor cells were capable of forming perfusable vessel-like networks through a process called vasculogenic mimicry (VM).
Metabolic studies investigating the mechanics of cancer cell proliferation have been critical to understanding resource allocation driving tumorigenesis. Generally, proliferating cells eschew efficient energy production in favour of metabolic pathways that generate the essential macromolecular building blocks necessary to grow in size and number, classically termed the Warburg effect.