An international consortium of scientists have found a way to produce a semi-synthetic strain of baker´s yeast with more than a third of its chromosomes artificially synthesized.
An international collaboration of scientists successfully produced a stable artificial strain of bacteria with an extended “genetic alphabet”. The microbe encompasses two additional “X” and “Y” nucleotides, which enable it to store increased information within its genome, laying foundations for new forms of life.
In 2010 John Craig Venter and his colleagues reported a creation of the first bacterial cell containing a completely synthesized genome. It was a 1.08-mega-base pair Mycoplasma mycoides JCVI-syn1.0 genome and it became the very first citizen of synthetic biology.
Over the last decade or so, the explosion in outputs of DNA sequencing, bioinformatics and modern molecular genetics opens the possibility of completely redesigning new crops from scratch.
A group of US and Canadian researchers conducted the largest-scale testing of folding stability for computationally designed proteins. More than 15,000 newly designed small proteins were tested for correlation between folding and function which resulted in significant protein modeling improvements.
US scientists discovered a surprising hidden function of mammalian lungs – they help produce blood. Their study on mice showed that more than half of all platelets in mice are produced by the lungs, a process long attributed to bone marrow.
The end of the year marks the time, when we take a look back at the memorable moments that make each year unique and think about what lays in store ahead. With the festivities reaching their peak, Splice would also like to review the important milestones that made 2016 a very special year.
A growing global epidemic of obesity and its related health complications such as type 2 diabetes is the reason why scientists are focusing on finding genes that increase the risk of developing obesity in the last decade. A breakthrough was finally made with discovery of the gene for ‘leanness’.
The combination of drug misuse, reductions in antimicrobial research by the pharmaceutical industry, and the rapid evolution capabilities of microorganisms has resulted in pathogenic bacteria with stronger and stronger drug resistance. This is an issue that some fear if not handled correctly, could lead to the evolution of a “superbug” that is resistant to everything in our arsenal.