One of the hottest trends in life sciences research for the past few years has been the development of subfields of study focused on specific, complex networks within biological systems. These subfields are quite recognizable due to the common suffix ‘-ome’, and there is now an exciting and extensive list of “omes” starting with arguably the grandfather of them all, the genome.
Extraction of DNA before its amplification is an essential step for the measurement of any DNA target. It releases the DNA and removes substances inhibitory to PCR that are initially present in the matrix.
Metabolic studies investigating the mechanics of cancer cell proliferation have been critical to understanding resource allocation driving tumorigenesis. Generally, proliferating cells eschew efficient energy production in favour of metabolic pathways that generate the essential macromolecular building blocks necessary to grow in size and number, classically termed the Warburg effect.
There are approximately 140 000 species of higher fungi. Only 10% of mushroom-forming species are known, making them an enormous untapped pool of potentially useful substances.
Since we live in the digital era, why shouldn’t a popular method like PCR go digital as well? What is digital PCR (dPCR) and how it is different in comparison to PCR and qPCR, has been explained in the webinar “Why go Digital in qPCR”.
A leader in genetic sequencing is betting that it can detect cancer at its earliest stages on the basis of minuscule amounts of genetic material circulating in a person’s bloodstream. But specialists warn that there are many technical hurdles to such an application.
Advances in gene editing technology have spurred considerable progress towards a treatment for Duchenne muscular dystrophy (DMD). Although the disease is rare – affecting roughly 1 in 5,000 male births – its consequences are devastating: patients are confined to wheelchairs at an early age and often succumb to heart or respiratory failure in their twenties or thirties.
Nowadays, magnetic beads are considered a powerful tool for a variety of research and medical applications. Coupling of magnetic properties with specific ligands in magnetic beads allows the separation and purification of cells, proteins, nucleic acids, and other molecules in a highly efficient and specific manner.
There is a lot of bad publicity around genetic engineering, especially when it comes to the genetic modification of plants and animals. Most opponents of genetic engineering claim that inserting foreign genes into other organism’s genome is unnatural and dangerous.