CRISPR (Clustered Regularly Interspaced Palindromic Repeats) gene editing technology allows permanent modification of genes within organisms. It is considered a breakthrough in biotechnology ever since its discovery. Researchers from the University of Copenhagen (Denmark), led by Spanish researcher Guillermo Montoya, now went one step further. They discovered how Cpf1, a new type of molecular scissors, unzip and cleave DNA.
The Francis Crick Institute of London was granted permission for genome editing in human embryos in order to study the complex processes involved in early miscarriage. This is the first time a research team has ever been exempt from the ban on human testing and represents an important step forward for science.
An international collaboration of scientists successfully produced a stable artificial strain of bacteria with an extended “genetic alphabet”. The microbe encompasses two additional “X” and “Y” nucleotides, which enable it to store increased information within its genome, laying foundations for new forms of life.
The end of the year marks the time, when we take a look back at the memorable moments that make each year unique and think about what lays in store ahead. With the festivities reaching their peak, Splice would also like to review the important milestones that made 2016 a very special year.
Disease Predictions and Our Genes – Are We Ready to Know? The Answer Lies in Three Important Factors.
The world is on the brink of an era of personalised medicine where genetics & genomics play a major role, but what about the patients? Are we there yet? Are we ready to perceive and to cope with the available information? Are we ready to know?
There is a new era rising in molecular biology and it began with CRISPR technology (Clustered Regularly Interspaced Short Palindromic Repeats), which is a genetic modification tool based on bacterial immune system. Gene drives is another interesting mechanism to use for altering genes but in contrast with CRISPR/Cas system it can only function in sexually reproducing species, leaving viruses and bacteria out of the picture.
Splice has been following the changes and improvements of Electronic Lab Notebooks (ELNs) for the past six months. This November (2016) we extended the list of Top 7 to Top 9 Best ELNs you can currently choose from. Our review is focusing on ELNs that offer the best price performance ratio for universities and research institutions.
Viruses, small infectious agents that replicate only inside the living cells of other organisms, have been around for billions of years. They can infect all types of life forms, from microorganisms, plants and animals to humans. It has been estimated that there are 10 to the power of 31 viruses on Earth, but humans don’t just live in a viral world, we are also part virus ourselves. Viruses actually comprise up to the 8% of the human genome and these so called endogenous retroviruses (ERVs) represent ancient viral infections that became integrated into the human genome.
Zika virus has rapidly expanded during the last year in Brazil and currently the outbreaks are occurring in several countries and territories. While following preventive measures is extremely important to limit the spread, finding a reliable field diagnostic test is equally important. And it looks like we got one!