US researchers just discovered a novel gene associated with amyotrophic lateral sclerosis (ALS) that compromises motor neuron function in mice and zebrafish. The UBQLN4 genetic variant impairs nerve development through the excessive accumulation of beta-catenin, a realization that opens a new window for targeted treatment of ALS.
Researchers at Harvard University developed an effective personalized cancer vaccine that seems to have prevented early tumour relapse in 12 skin cancer patients. The vaccine targeted 20 tumour-specific proteins unique to each of the patients enrolled, keeping all free of cancer over 2 years after the trial.
Extensive observational studies, surveys and meta-analysis moved scientists a step closer to understanding how highly-educated people can still contradict scientific facts. The result is a refined guide to effectively addressing skeptics, and it´s not based on presenting evidence, but rather identifying their underlaying motivation.
The end of the year marks the time, when we take a look back at the memorable moments that make each year unique and think about what lays in store ahead. With the festivities reaching their peak, Splice would also like to review the important milestones that made 2016 a very special year.
Every living being on Earth is a part of a giant network where different species depend on each other for survival. This natural system is very complex and built of many different networks where different species interact with each other.
As we are approaching the end of the year, it fits to wrap up Splice’s achievements in 2015.
Splice blog was launched in March 2015 with the idea to provide life scientists with some easy reading during their coffee break, hence the slogan “Coffee Break News for Life Scientists”. It exhibits high quality articles, written by life science experts specialized in various scientific fields.
Over 60% of retracted scientific articles are retracted due to unintentional errors.
Can we trust your published qPCR data?
The pressure to publish is causing shortcuts which result in misleading papers being published.