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Scientists from Europe and the U.S. have managed to restore hearing in an adult mouse model. The mice suffered from so-called DFNB9 deafness, a genetic hearing disorder that represents one of the most frequent causes of congenital deafness. These findings could open doors to new gene therapies for other forms of deafness.
Alzheimer´s disease is the most prevalent form of dementia and represents one of the puzzles in modern medicine. The condition was treated merely symptomatically to date, however a new animal study shows that delivering a specific gene to the brain could be used to treat it systematically.
A next-generation of antivenom could be just around the corner. Besides being safer and more effective, the technology behind it can also be applicable for other diseases, such as cancer and COVID-19.
A new gene therapy approach developed at St. Jude Children’s Research Hospital has cured infants born with X-linked severe combined immunodeficiency (SCID-X1), known as “Bubble Boy” disease. The patients recovered with fully functioning immune systems and started producing immune cells, including T cells, B cells, and natural killer (NK) cells. The researchers achieved that by hijacking the […]
Researchers developed a new approach to cell therapy that uses nanoparticles to deliver genetic material that induces changes in the cell´s transient gene expression. An approach that is faster and cheaper to develop, more customizable and as simple as ‘just add water’.
Scientists have managed to completely eliminate the HIV virus in living mice using the revolutionary CRISPR/Cas9 gene-editing technology. They have demonstrated how it excises the viral DNA from the host animal and prevents further infection, providing hope that it could one day benefit humans.
A new breast cancer drug combination significantly shrunk and eliminated tumours in 28% of women tested in just 11 days. The novel treatment involves a combination of pre-chemotherapy drugs lapatinib and trastuzumab that target HER2-positive tumours.
Scientists developed a strain of Salmonella that fights aggressive brain cancers which produced a remarkable 20% rate of tumor remission in a rat model, where there are normally no survivors. The bacteria were genetically equipped with a sophisticated tumor-homing mechanism along with cancer fighting weapons, causing the tumors to effectively self-destruct.
Scientists have discovered an effective stem cell treatment to battle bone loss, that could help regenerate bones of osteoporosis patients and even astronauts. The novel therapy showed remarkable results in mice and is expected to enter human clinical trials in the next two years.
While bacterial infections usually are a bad thing, they can now be used as a therapy to treat medical conditions, for instance, cancer.
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