Zebrafish have become the animal model of choice for research in many areas. Now, researchers from Rice University trace roots of cancer development using genetically modified zebrafish. These fish produce fluorescent tags in migratory embryonic nerve precursor cells, enabling them to trace neuroblastoma and other forms of cancer.
Researchers from Arizona State University and the Icahn School of Medicine at Mount Sinai Indiana University made a large-scale analysis and used data from three different brain banks. They concluded that human herpes viruses are more abundant in the brains of Alzheimer’s patients and may play a role in regulatory genetic networks believed to be behind the onset of the disease. New possibilities for Alzheimer’s treatment, such as antiviral and immune therapy, are now open.
Men are still limited to only a few forms of birth control. Scientists are making constant progress but the birth control pill or any other hormonal contraceptives for men are still years away from being safe, reversible, and broadly available. In the past, low demand and focus on women contraceptives partly limited development. Now, more and more men want to take control over their own fertility.
Researchers from Indiana University (IU) have made the first direct visual observation of bacteria taking up foreign DNA from its surrounding. It is a key step in their process of rapidly evolving new traits, including troublesome drug resistance. The new methods developed by the researchers provided them with the ability to catch this mechanism on film.
Researchers from the University of California have programmed synthetic cells to mobilize nearby natural cells into complex structures. At first, individual cells self-organized into multi-layered structures resembling simple organisms or the tissues from the first stages of embryonic development. The technology could have a bright future in repairing damaged tissue or re-growing injured organs.
Engineers from the University of Illinois built a 3D printer that produces a delicate network of thin ribbons of hardened sugar alcohol, isomalt. These detailed biological structures are water-soluble, biodegradable glassy structures that could have multiple applications in biomedical engineering, cancer research, and device manufacturing.
Researchers from UCLA successfully transplanted memories by transferring RNA from one sea snail into another. They are one step closer to solving the puzzle of the physical basis of memory. In the long run, these findings could lead to treatments of diseases such as Alzheimer’s or post-traumatic stress disorder (PTSD).
Researchers from the Netherlands have found a way to “grow” artificial mouse blastocysts by combining different stem cells in a dish. The artificial embryos resemble natural ones so closely that, when transferred into a mouse’s uterus, they initiate pregnancy. They can easily be mass-produced and could serve as new models for drug development, possibly leading to infertility treatments and early interventions for other diseases.
Researchers from China have modified an Artemisia annua genetic sequence to produce a higher level of a potent antimalarial compound, artemisinin. The group identified genes involved in making artemisinin in Artemisia annua and altered their activity to produce three times more drug than usual. Their work will help to meet the large global demand for artemisinin, which is also used to treat cancer, tuberculosis, and diabetes.
New research suggests that some of the additives that extend the shelf life and improve the texture of processed foods may have harsh side effects on the human gut microbiome. The rise in deadly cases of a terrible gut infection caused by Clostridium difficile is the outcome of adding the sugar trehalose to almost all of our processed food.