Category : MOLECULAR BIOLOGY AND GENETICS

bacteria

Bacteria “Harpoon” DNA To Speed Up Their Evolution

Researchers from Indiana University (IU) have made the first direct visual observation of bacteria taking up foreign DNA from its surrounding. It is a key step in their process of rapidly evolving new traits, including troublesome drug resistance. The new methods developed by the researchers provided them with the ability to catch this mechanism on film.

synthetic tissues

Synthetic Tissues That Build Themselves

Researchers from the University of California have programmed synthetic cells to mobilize nearby natural cells into complex structures. At first, individual cells self-organized into multi-layered structures resembling simple organisms or the tissues from the first stages of embryonic development. The technology could have a bright future in repairing damaged tissue or re-growing injured organs.

embryo

Artificial Embryos Made From Stem Cells Initiate Pregnancy in Mice

Researchers from the Netherlands have found a way to “grow” artificial mouse blastocysts by combining different stem cells in a dish. The artificial embryos resemble natural ones so closely that, when transferred into a mouse’s uterus, they initiate pregnancy. They can easily be mass-produced and could serve as new models for drug development, possibly leading to infertility treatments and early interventions for other diseases.

mosquito malaria

Engineered Shrub Boosts Malaria Drug Artemisinin Yield

Researchers from China have modified an Artemisia annua genetic sequence to produce a higher level of a potent antimalarial compound, artemisinin. The group identified genes involved in making artemisinin in Artemisia annua and altered their activity to produce three times more drug than usual. Their work will help to meet the large global demand for artemisinin, which is also used to treat cancer, tuberculosis, and diabetes.

Processed Food

Sugar Additives Might be Feeding Aggressive Superbugs

New research suggests that some of the additives that extend the shelf life and improve the texture of processed foods may have harsh side effects on the human gut microbiome. The rise in deadly cases of a terrible gut infection caused by Clostridium difficile is the outcome of adding the sugar trehalose to almost all of our processed food. 

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