Researchers from the University of California have programmed synthetic cells to mobilize nearby natural cells into complex structures. At first, individual cells self-organized into multi-layered structures resembling simple organisms or the tissues from the first stages of embryonic development. The technology could have a bright future in repairing damaged tissue or re-growing injured organs.
Engineers from the University of Illinois built a 3D printer that produces a delicate network of thin ribbons of hardened sugar alcohol, isomalt. These detailed biological structures are water-soluble, biodegradable glassy structures that could have multiple applications in biomedical engineering, cancer research, and device manufacturing.
Researchers from UCLA successfully transplanted memories by transferring RNA from one sea snail into another. They are one step closer to solving the puzzle of the physical basis of memory. In the long run, these findings could lead to treatments of diseases such as Alzheimer’s or post-traumatic stress disorder (PTSD).
Researchers from the Netherlands have found a way to “grow” artificial mouse blastocysts by combining different stem cells in a dish. The artificial embryos resemble natural ones so closely that, when transferred into a mouse’s uterus, they initiate pregnancy. They can easily be mass-produced and could serve as new models for drug development, possibly leading to infertility treatments and early interventions for other diseases.
Researchers from China have modified an Artemisia annua genetic sequence to produce a higher level of a potent antimalarial compound, artemisinin. The group identified genes involved in making artemisinin in Artemisia annua and altered their activity to produce three times more drug than usual. Their work will help to meet the large global demand for artemisinin, which is also used to treat cancer, tuberculosis, and diabetes.
New research suggests that some of the additives that extend the shelf life and improve the texture of processed foods may have harsh side effects on the human gut microbiome. The rise in deadly cases of a terrible gut infection caused by Clostridium difficile is the outcome of adding the sugar trehalose to almost all of our processed food.
Stanford University bioengineers have found a way to produce noscapine, a non-narcotic cough suppressant with potential anticancer properties, in brewer’s yeast. The researchers inserted 25 foreign genes into the yeast to turn it into an efficient factory for producing the drug that naturally occurs in opium poppy.
Commonly prescribed drugs called fluoroquinolones, the fourth-most used class of antibiotics in the US, have been shown to cause rare, disabling side effects. Patients have experienced pain in tendons, joints and muscles, neurological and psychological difficulties. Researchers now have a few theories why such symptoms may occur.
An international clinical study demonstrated astounding recovery of patients with multiple sclerosis after a stem cell transplant. Scientists claim these transplants are dramatically better than standard drugs at halting the spread of multiple sclerosis and improving its symptoms.
New research reveals genetic mysteries behind synesthesia – a condition in which different senses seem to be crossed up in the brain, causing a person to “taste” words or even “feel” numbers. The phenomenon has been intriguing neuroscientists for years and this research could unlock new doors to understanding how our brains process sensory input.