Researchers have taken an interest in a euphorbia plant growing in Marocco as a possible painkiller. The plant’s active ingredient, resiniferatoxin (RTX), is extremely spicy, a 10,000 times hotter than the world’s hottest pepper. RTX is a potent analog of capsaicin, the active ingredient in chilli peppers, and has numerous benefits over existing painkillers. It doesn’t require frequent dosing, targets only the areas causing pain, and doesn’t produce a potentially addictive high. All this makes it a promising candidate for the clinics.
An international team of researchers detected a vast sixty-nine pharmaceutical compounds in stream insects. When these insects emerge as flying adults, they can pass these drugs further to spiders, fish, birds, bats, and other streamside foragers. This way, drug pollution moves up food webs and in some cases exposes even top predators to therapeutically-effective doses.
Researchers from McMaster University in Canada have engineered “smart” surface coatings that can repel almost everything, including bacteria, viruses, and living cells. A new feature of this technology is the possibility of modifying the coating to permit beneficial exceptions. These surfaces create the promise of safer implants and more accurate diagnostic tests.
Food scientists from Cornell University have developed a test for rapid detection of E. coli in drinking water using genetically-engineered bacteriophages. It can be administered locally in hard-to-reach areas around the world and provides results within hours. Obtaining quick and accurate results is a current bottleneck in preventing infection and could save many.
Researchers from Stanford have identified human skeletal stem cells that become bone, cartilage, or stroma. Cells were recovered from fetal and adult bone marrow and were also derived from induced pluripotent stem cells. This discovery will open up new therapeutic possibilities.
Australian researchers have shown for the first time that laser therapy can be used to alter the population of gut bacteria in mice. The findings, if confirmed in humans, could help in the treatment of diseases such as diabetes.
Almost 20 years ago the human genome, 3 billion DNA base pairs long, was first sequenced. Despite all the progress researchers still know little about how the genome is organized within cells. Now researchers from the University of Illinois at Urbana-Champaign have developed a new technique that can create a 3D image of the genome’s organization.
Researchers from the University of Copenhagen used a new advanced technique to identify a protein that is responsible for cellular memory transfer in cell division. The finding is decisive for a fresh view and understanding of development from one cell to a whole body.
Researchers from The University of Toledo have found the chemical reason behind why blue light damages our eyes over time, contributes to macular degeneration, and can even cause blindness. Since we’re spending more time in front of screens than ever before, this finding might be a big step forward toward preventing eyesight deterioration.
Two separate research groups used CRISPR gene editing to fuse entire sets of brewer’s yeast chromosomes together, resulting in two strains with just one and two chromosomes. Surprisingly, the changes had little effect on most functions of the yeast. Their findings could be monumental to the study of chromosomes and why their numbers vary from species to species.