The heated legal war over the ownership of the revolutionary CRISPR/Cas9 gene-editing technology has finally reached a verdict. The US Patent and Trademark Office (UPTO) concluded that evidence favored the Broad Institute of MIT and Harvard for most patents rather than UC Berkeley, the technology´s initial inventor.
Researchers from Harvard University announced their plan to bring the woolly mammoth back to life using CRISPR/Cas9 within two years’ time. This would not only allow us to learn more about the prehistoric behemoth, but would also represent a first step towards preservation of endangered species.
Scientists developed a strain of Salmonella that fights aggressive brain cancers which produced a remarkable 20% rate of tumor remission in a rat model, where there are normally no survivors. The bacteria were genetically equipped with a sophisticated tumor-homing mechanism along with cancer fighting weapons, causing the tumors to effectively self-destruct.
Researchers claim they have debunked a long-standing misconception of the mathematical model of human mortality that predicts a set limit on aging. Their discovery comes as good news in a time of increasing breakthroughs in anti-aging therapy.
Scientists have discovered a way to activate dormant predatory centers in mice using optogenetics, causing them to go rogue and revert to hunter-associated behavior. This was achieved with stimulation of a specific pair of neurons in the brain, providing a glimpse of how the predatory behavior could have evolved over millions of years.
An international collaboration of scientists successfully produced a stable artificial strain of bacteria with an extended “genetic alphabet”. The microbe encompasses two additional “X” and “Y” nucleotides, which enable it to store increased information within its genome, laying foundations for new forms of life.
USDA approved the sale of genetically modified (GM) apples that “stay fresh” up to three weeks after being sliced or bruised, which are expected to enter stores by March. This comes as an answer addressing the major problem of wasting apples, with nearly 40% of them being discarded due to superficial bruising and browning.
Developer of NGS devices Ilumina claims its new NovaSeq instrument will soon manage to sequence a person´s entire genome for less then $100 in as little as 60 minutes. This would represent a marginal improvement from the current benchmark, which stands at roughly $1,000.
Researchers from Johns Hopkins University successfully modified mosquitoes to render them highly resistant to dengue virus – a disease responsible for nearly 25,000 deaths each year. Their breakthrough could lead to even more resistant mosquitoes in the future, potentially ending the war on mosquito-transmitted diseases.
Researchers at the University of Michigan developed an impressive new way of delivering customized therapeutic cancer vaccines using antigen-carrying nanodiscs. The treatment showed excellent success in mice, drastically decreasing the occurrence of colon and melanoma tumours.