Researchers from the University of California tested gene-drive technology in mice. This controversial application of CRISPR, capable of altering the genomes of entire species, has been applied to mammals for the first time. Although the developed technology has a long way to go before being used for pest control in the wild, it could be useful in basic research.
Zebrafish have become the animal model of choice for research in many areas. Now, researchers from Rice University trace roots of cancer development using genetically modified zebrafish. These fish produce fluorescent tags in migratory embryonic nerve precursor cells, enabling them to trace neuroblastoma and other forms of cancer.
Researchers from Arizona State University and the Icahn School of Medicine at Mount Sinai Indiana University made a large-scale analysis and used data from three different brain banks. They concluded that human herpes viruses are more abundant in the brains of Alzheimer’s patients and may play a role in regulatory genetic networks believed to be behind the onset of the disease. New possibilities for Alzheimer’s treatment, such as antiviral and immune therapy, are now open.
Men are still limited to only a few forms of birth control. Scientists are making constant progress but the birth control pill or any other hormonal contraceptives for men are still years away from being safe, reversible, and broadly available. In the past, low demand and focus on women contraceptives partly limited development. Now, more and more men want to take control over their own fertility.
Perhaps one of the most interesting parts of an organism to study is its brain, as it can be thought to be at the core of identity. The brain allows for complex functions such as memory and associations to exist. Evolutionarily, this has allowed for social interactions to form the basis of groups and eventually allow for large numbers of individuals to live together in communities.
Researchers from Indiana University (IU) have made the first direct visual observation of bacteria taking up foreign DNA from its surrounding. It is a key step in their process of rapidly evolving new traits, including troublesome drug resistance. The new methods developed by the researchers provided them with the ability to catch this mechanism on film.
Researchers from the University of California have programmed synthetic cells to mobilize nearby natural cells into complex structures. At first, individual cells self-organized into multi-layered structures resembling simple organisms or the tissues from the first stages of embryonic development. The technology could have a bright future in repairing damaged tissue or re-growing injured organs.
Engineers from the University of Illinois built a 3D printer that produces a delicate network of thin ribbons of hardened sugar alcohol, isomalt. These detailed biological structures are water-soluble, biodegradable glassy structures that could have multiple applications in biomedical engineering, cancer research, and device manufacturing.
Rather than relying on serendipity to discover novel therapeutics, today we can work intelligently to identify antibodies that target exactly what we desire. Our immune system has been refined through millions of years of evolution, and our ability to harvest its capabilities now allows us to develop intelligently designed antibody-based medicines. This new generation of biotherapeutics holds great promise in tackling diseases and conditions that were previously untreatable.
Researchers from UCLA successfully transplanted memories by transferring RNA from one sea snail into another. They are one step closer to solving the puzzle of the physical basis of memory. In the long run, these findings could lead to treatments of diseases such as Alzheimer’s or post-traumatic stress disorder (PTSD).
