COFFEE BREAK NEWS FOR LIFE SCIENTISTS

mosquito malaria

Engineered Shrub Boosts Malaria Drug Artemisinin Yield

Researchers from China have modified an Artemisia annua genetic sequence to produce a higher level of a potent antimalarial compound, artemisinin. The group identified genes involved in making artemisinin in Artemisia annua and altered their activity to produce three times more drug than usual. Their work will help to meet the large global demand for artemisinin, which is also used to treat cancer, tuberculosis, and diabetes.

viagra

Cancer-Fighting Cure Could Hide in the Last Pill You Would Think Of

The class of drugs currently prescribed to treat male erectile dysfunction has the potential to be repurposed for use in cancer treatment. Cancer specialists would like to prescribe existing medications like Viagra and Cialis since they are affordable and approved for use, thus save significant research money otherwise spent on expensive drug discovery.

poppy

Yeast Bioengineered to Produce Poppy-Based Medicine

Stanford University bioengineers have found a way to produce noscapine, a non-narcotic cough suppressant with potential anticancer properties, in brewer’s yeast. The researchers inserted 25 foreign genes into the yeast to turn it into an efficient factory for producing the drug that naturally occurs in opium poppy.

Snake venom

Venoms That Save Lives

It is common knowledge that the venom from a snake or scorpion can be dangerous. Less known is the fact that several drugs are derived from the toxins of venomous animals. Throughout history, humans have used toxins for medical purposes. Today, modern medicine uses the vast amount of toxins as inspiration for developing novel drugs. Despite the potential of venom-derived drugs, only seven have been approved so far.

antibiotic

When a Popular Class of Antibiotics Turns Toxic

Commonly prescribed drugs called fluoroquinolones, the fourth-most used class of antibiotics in the US, have been shown to cause rare, disabling side effects. Patients have experienced pain in tendons, joints and muscles, neurological and psychological difficulties. Researchers now have a few theories why such symptoms may occur.