A new gene therapy approach developed at St. Jude Children’s Research Hospital has cured infants born with X-linked severe combined immunodeficiency (SCID-X1), known as “Bubble Boy” disease. The patients recovered with fully functioning immune systems and started producing immune cells, including T cells, B cells, and natural killer (NK) cells. The researchers achieved that by hijacking the HIV virus to replace the mutated gene, called IL2RG, with a corrected copy.
Scientists from Washington University in St. Louis have found a new method to genetically alter bacteria and acquire super-strong spider silk. Farming spiders is incredibly inefficient and finding a way to mass-produce the material would bring us a step away from a ready supply of incredibly resilient fabrics. The method could clear the way for the production of other scarce proteins that could even be used for future space missions.