Splice has been actively following the changes and improvements of the Electronic Lab Notebooks (ELNs) landscape to provide you the latest information. This April (2018) we updated our list of the Top 9 Best ELNs you can currently choose from. Our review is focused on ELNs that offer the best price-performance ratio.
ELNs from companies such as PerkinElmer, Agilent Technologies, BIOVIA (formerly known as Accelrys) and IDBS are missing from the list because their features are more appropriate for regulated environments and are often too expensive for academic labs. At the moment there areover 100 ELNs available to researchers. In this updated article, we are focusing on the top 9 of available ELNs that fit our criteria. Reviews can be seen below.
Paper-based lab notebooks
It is no secret that the paper-based laboratory notebook is the most widely used form of experimental data tracking in labs worldwide. It’s been around for several centuries (even da Vinci had one) and you will find it in the cabinet of every scientist. But does that necessarily imply that it’s also the most efficient way of recording scientific data?
Experimental records that aren’t being digitized account for 17% loss of all research data and lab books are becoming the bottlenecks in information management. This poses great repeatability threats, enormous costs and considerable limitations for knowledge sharing within an organization and the community.
To be fair, paper lab books seemed to have done the job pretty well so far and there are many features that make it great; e.g. they´re inexpensive and don’t require batteries to run. Yet there are only a few things we have not modernized for over a century, let alone a millennium. Technological advances simply make things better and you won’t find anyone doing their taxes on an abacus.
A glimpse of the future
Automation and digitization enabled researchers to achieve outputs like never before imaginable. With hundreds of emerging knowledge-sharing platforms, data can now be distributed globally before you can say “DNA”. The integration-based approach has allowed science to flourish and interoperability is swiftly becoming the new buzzword in modern research. Imagine all your instruments sending analytical data directly into a single software platform. No more running around with USB sticks, copy-pasting, printing, cutting and glueing. Please, do tell more.
Introducing the Electronic Lab Notebook (ELN)
ELN stands for Electronic Laboratory Notebook but it spans far beyond just a replacement for paper. It brings forth systematical, safe, and efficient data storage along with interoperable data distribution.
The majority of the recently developed ELNs are set up as cloud-based software (like Dropbox), which means, that researchers can also seamlessly collaborate in real time, eliminate tedious manual data exchange and overcome hurdles in communication. And best of all, an ELN doesn’t have to stay locked up in the lab when you leave.
Did I mention that electronic lab notebooks (ELNs) are coffee-proof?
Since 2000, when worldwide governments issued laws granting all electronic records the same validity as paper records, the number of available ELNs increased exponentially. Today, approximately 11% of labs already started implementing ELNs with an additional 75% showing interest in the technology. The fact that these numbers keep rising with every update to this article (annually) is a very good sign for ELNs and science in general. Yet naysayers remain, who often claim that using paper is easier than its electronic counterpart. But is it really? Universities conduct whole courses on paper lab book documentation – just look at this lab notebook maintenance manual from Columbia University and decide what is easier for yourself.
Whatever your stance on electronic lab notebooks may be, it is clear that a digital revolution is at our doorstep. With over 60 ELNs out there, it is really hard to decide where to even start. That is why we rounded up the 9 very best ELNs that will make your transition easier for when you choose to take that red pill.
Our criteria – ELN features under the magnifying glass
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USER EXPERIENCE
Graphical user interface (GUI)
Intuitiveness
Support (on-line support, available manuals and video tutorials)
INTEROPERABILITY AND FLEXIBILITY
Multi-device compatibility
Working with different operating systems and browsers
Each lab has its own set of expectations, intents, and capabilities, which will most likely never be fully met by a single universal ELN. Open source electronic lab notebooks provide a perfect solution, as they can be customized for specific applications and further inspire innovation from the community of end users. Free electronic lab notebooks also have higher adoption rates compared to those that have no option for a free user account as users take no risk by paying for something which at the end they don’t like.
Labs of the future will indisputably rely on interoperability of their instruments and devices. I believe that ELNs we have listed here will be capable to stand the test of time as they are already compatible with smartphones and tablets. The instruments will follow next.
Conclusion
It´s an exciting time to be a researcher. We are witnessing a digital revolution of science and we´ll get to explore the benefits it brings. The electronic laboratory notebook is at the helm of the revolution when it comes to labs and a much-needed breath of fresh air in experimental data management. There are now several great ELNs to choose from, each providing its unique set of tools to make your work easier and more effective. I hope this review will help you choose yours and make a step towards a digital tomorrow.
By Luka Zupancic MSc, University of Applied Sciences Technikum Vienna
*Splice is a scientific news blog funded by BioSistemika LLC, a software development company that also co-founded sciNote LLC (free open source ELN). All of the ELNs included in this review were scored by an independent author and researcher, based on the major criteria identified in the largest study on user perception of electronic lab notebooks ever published, to provide the most relevant and objective insights for our readers. The author states that the views and opinions are entirely his own.
Security aspect should be a key factor when making decision concerning this kind of products, especially if you’re either doing research that has potentially commercially valuable results (your research contract may actually require you to take specific precautions) and/or your data is sensitive as defined in the legislation (think EU GDPR, that covers humane genetic data, for instance).
So true! Although the criteria used in this review to score the ELN’s are important, we (as provider of the Electronic Lab Notebook eLABJournal), are challenged by our customers every day to show that we provide a secure ELN solution. Besides supporting essential security features, such as enforcing password policies and two-step verification, ISO27001 certification of the vendor is essential to show that security is priority and that measures to safeguard the data of customers are in place. Also, offering the flexibility to choose between hosting of the software in the cloud or on own servers (yet the option to switch at any time), is important to comply with strict security policies of organizations which do not permit the use of cloud hosted solutions.
Another good one that is not as well-known yet but has many of these desired features is CERF. It comes from the same company as RSpace, is desktop-based (meaning it can be used offline), and has one of the better search engines anywhere to find information you put in years ago. If you need to be 21CRF11 compliant as well, it has got that covered. The only real disadvantage is that the GUI looks like it’s from the early 2000’s, but it is still something I wish I had in college back in 2014, espcially in chemistry class. The 3-D models of molecules are cool!
by Eileen SullivanScully ,
post on 9 September 2018 |
Reply
A GMP Life Science Manufacturing environment needs a 21 CFR 11 Compliant solution. FDA Regulatory GMP Pharma, BioTech & Medical Device manufacturing plants use OpsTrakker E-Logbook Solution by Enhanced Information Solutions out of Stillwater MN.
I would like to point out that Docollab is compatible with mobile devices. It has been tested with Chrome, Firefox and Opera on Android, and Safari on iOS.
I’m not sure what “Not possible to write comments” mean, but Docollab does provide a rich document editor in which you can write pretty much anything, including comments, and review past revisions of the document. Furthermore, it provides a task management feature in which you can add comments to tasks.
We would appreciate if these details could be updated. If you have any more questions, you are welcome to contact us at
thank you for your comment. It´s possible that some functionalities have been updated since I last tried out Docollab. I will definitely consider the features you mentioned for my next update of the article. Appreciate your help, will reach out if I encounter any questions in the process.
Hi Luka,
do you care to point out that you are the brother of Klemen Zupančič who is a Business Development Executive with biosistemika (https://biosistemika.com/team/), the company that offers SciNote and is magically rated first place here?
I think the conflict of interest is quite obvious here – and luckily, most researchers try out different softwares and are able to draw their own conclusions – which in many cases, result in a quite different ranking than the one postulated here.
thank you for your comment and for bringing up the question. As I pointed out several times below, the article reflects my professional opinion as a scientific researcher and is by no means a representation of a larger cohort of people or an organization for that matter. It´s an inherently personal view I firmly stand by, shaped by a great deal of effort invested in trying out numerous ELNs including your company´s ELN labfolder. If nothing else, my signature under this review should be a clear testament of my intent and good faith.
I feel it´s needles to say that different people would have scored it differently, I absolutely agree with you on that notion. I openly welcome all comments, experiences, and opinions surrounding the ELNs in question and had previously updated the scores based on constructive feedback from the comments.
I think it’s a bit surprising that the author didn’t just say “Yes he’s my brother” or “No he’s not”.
Declaring the conflict of interest doesn’t mean your opinion is invalid. A conflict of interest may be more perceived than real or may have effects on you that are not conscious. Sometimes declaring a perceived or possible conflict of interest will actually increase your credibility because readers can respect the fact that you have considered and disclosed possible sources of bias.
As scientists it is important to disclose conflicts of interest even if we genuinely believe that we are not affected by them.
by Costas Bouyioukos ,
post on 3 September 2017 |
Reply
Good point James!
Instead of writing two paragraphs of “needless to say” things, a simple answer “yes” or “no” would have sufficed and definitely improve the credibility of the post.
However, the signature clearly states that the blog is sponsored by biosistemika, which is a quite fair statement too.
I personally have contacted each ELN venders and have them demoed to me, it took me more than two months. One of the outstanding ELN that not seeing here is the Labii ELN. You will be amazed how it different to all other existing ELNs in both design and functions and how it can link the experiments, protocols, samples, reagents, et.al all together. I specifically like it to be able to extract the metadata from lab note for statistic data analysis. You can find it at this link: https://www.labsexplorer.com/c/2017-review-of-best-electronic-laboratory-notebooks_6
Hi Young Wu, appreciate your feedback! Labii does seem like an interesting option after a quick inspection, however I would need to examine it first-hand before commenting on its functionality and usability further. For now, the information provided on the product website seems rather scarce. Nevertheless, I would happily consider reviewing Labii in a possible update to this review.
Hi Luka, Do you have a chance to review it? Our company is using Labii. It is just released a new version. I like it for the freedom to customize what data to store, what column to have and what details to insert. It also introduces the concept of widgets, which enables adding the functions to meet each lab’s requirement. My favorite part is pay-per-use. I only pay for the records I created.
It has 5th biggest ELN and LIMS market/visibility based on SEMrush, which are much higher than Benchling and Scinote.
by Santi Dominguez ,
post on 13 March 2017 |
Reply
Hi, Luka,
Thank you for the article and for reviewing Mbook (I am the CEO of Mestrelab, anyone reading my comment should be aware of that).
I wanted to comment to point out a couple of inaccuracies.
Firstly, Mbook does have a free 45 day account, for those that want to try it out. Your reason to give a significant amount of weight to price is the fact that researchers like to try before they buy. This is certainly possible with Mbook. Of course, whether a 45 day or a 10 GB trial are more extensive, depends on the number of users and on the amount of data that is stored in the ELN.
Secondly, Mbook has indeed an in-house installation, as highlighted on our website. It is designed as a Cloud Solution, but we make available an installer for in-house installation to any institutions not happy putting their data on the cloud.
Finally, intuitiveness of interface is a subjective matter, and therefore I cannot really comment on your evaluation there. Mbook is designed for synthetic chemistry, and it makes sense to evaluate it from that viewpoint. It is aiming at making the creation of reactions, stoichiometry tables, experimental protocols and the attachment of analytical and other data to experiments as simple as possible. Of course, that may not work so well for other workflows or use cases, which it is not targeted to doing. From a synthetic chemist perspective, I would expect that structure editor, structure search, integrated inventory, self populating stoichiometry tables and immediate access to all analytical data are all points to value, which do not seem to be considered on your review, so this might be a point worth making.
thank you for your feedback, I appreciate you taking the time. Allow me to comment on the points you highlighted.
1) The »Free version« score refers to weather a free version of the software exists, which can be used continuously and not merely tried out. I do not see a 45-day account option as a free version but rather as a trial, which is also how it is advertised on your web page. However, I did appreciate the trial version and did award Mbook a respectable 4/5 points in the »Business model and Pricing« category.
2) I now understand you offer an in-house installation and I appreciate you bringing that up for the readers. This seems to be an honest mistake on my part, however I do recall that feature was not communicated very clearly at the time of my testing. I would be happy to take it into account in the upcoming update of this review.
3) You put it well and there is not much left to be said. The UX is in its nature a subjective matter and I´m positive people with different backgrounds would score differently. However, I did focus on aspects that make an ELN user friendly to a broader range of users (i.e. researchers), and not a very specific segment. I am not a synthetic chemist and did find myself frequently stumbling over hurdles in design that unfortunately diminished my experience with Mbook.
I would like to state that Mbook did prove as a valid candidate and I definitely see it as a solid ELN. That´s why I included it on the »Top 9« list, among many others that did not do the job as good.
Hi Paul, thank you for your comment, this has already been discussed bellow. Posting my reply again for your convenience:
“As a researcher frustrated with the limitations of paper lab books, I´ve been looking for an ELN for quite some time. In the process I also tried out sciNote and even participated in it´s beta testing phase. It was the last ELN I tested and it proved to best fit my needs.
Having finally found my ideal solution, I volunteered to write a piece about my journey of finding an ELN for Splice, to show my support and to help others in the same frustrating situation I was in for so long. The article offers an overview of the ELNs I’ve tried, as well as my personal evaluation of them.
Splice is an independent blog with contributions coming mainly from independent researchers from various institutions, such as myself. I still use sciNote every day and I firmly stand by my opinion, expressed in this article.”
Although your justification is reasonable, there is a lack of unbias analysis. For example:
In INTEROPERABILITY AND FLEXIBILITY section you mentioned 5 bullet points:
Multi device compatibility
Working with different operating systems and browsers
Cloud
Real-time collaboration
Instrument integration and open APIs
I personally tested LabArchives and Labfolder and both meet all the requirements, but end just with 3 out of 5.
Curiously, scinote does not offer an API (according to their own FAQ) and lacks dedicated mobile apps (there is just a shortcut option as they mention here https://scinote.net/product/mobile/) but they still had a better evaluation in that category 🙂
You bring up a valid point there and I do agree with you, everybody is entitled to their own opinion and many people would have surely scored the ELNs differently, based on their own needs and experiences.
In terms of interoperability, mine were not the best with LabArchives and Labfolder at the time of testing. Please note that this article is a second revision of the original one, and it could very well be that both products experienced updates in that area since then. However, if you scroll down you will find other people reported interoperability issues with the ELNs in question as well.
You are spot on regarding sciNote, those limitations are on point and did land them a lower score. Since their mobile version actually worked great for me and still does, I only deducted one point for the lack of an API.
I am surprised to not see the Findings app amongst these! I have just tried sciNote and I would say that the user experience of Findings the the functionality it offers are far superior. You would need to pay for a license, but I definitely think it’s more than worth it!
by Luka Zupančič ,
post on 23 February 2017 |
Reply
Hi Stelios, appreciate your feedback! Findings ELN does seem like an interesting pick after a quick inspection, however I do realize it is only available for iOS systems. I run all experiments in a PC setting and generally find solutions that are limited to a single platform disadvantaged. If a PC version comes out any time soon and an update to this review ever occurs, I would be happy to give Findings a try.
by Christoph Seiler ,
post on 20 February 2017 |
Reply
FINDING AN ELN (DUMPING SCINOTE)
Thanks for putting a list of these together, this seems to be the only place on the www that has some comprehensive review of ELNs. I run a research core and we do several projects for multiple labs and we really need an ELN. I am just testing a few, and hopefully will find time to write more about my impressions and final choice.
I wanted to comment about the ratings in this review: I believe that pricing is largely over-emphasized here, a product that takes more work to create will obviously create more costs and be more expensive. User experience also seems to lean towards simple programs, it seems that more complex ELNs with more modules are rated poorly just because it took the reviewers more time to understand the different parts. If an ELN will be used for standard operations am am willing to pay for it and spend some time to learn how to use it.
I believe that is what put the rather bare-bones ELN “SCINOTE” on top of the list. SCINOTE is the first one I dis-regarded, yes their licensing is free for most and sharing is somewhat easy, but recording procedures is frankly a pain. There is no way to add tables and calculation formulas, no annotation of result files, no sketching and no repository to organize reagents that are created.
by Luka Zupančič ,
post on 27 February 2017 |
Reply
Hi Christoph, thank you for your input! You bring up a good point, not all of the ELNs and their features in this review are equally important for everyone. Obviously expectations from lab to lab and researcher to researcher will differ and you highlighted some very good examples of that.
I tested the ELNs based on personal requirements, which I believe resemble those of a “typical researcher”. I needed a solid and reliable ELN solution to solve my everyday issues with experimental design and laboratory data management for a reasonable budget. I defined the scoring criteria to best represent those needs, which I believe correlate to a much larger portion of researchers out there. However, I absolutely agree with you, if the criteria were set in a different manner, the outcome would undoubtedly differ accordingly.
Great review. Rspace looks well adapted to academic labs from my cursory review. Glad to hear others work as well.
As someone who works across campus, and bridging researchers and facility managers I see the frustration of overfilled freezers and abandoned freezer contents when scientists retire. Facilities and office of research might support the costs of enterprise installations if ELN and sample management databases include expiration date defaults (that may be updated). This would enhance discarding of expired, forgotten or spoiled samples, which may comprise 30% or more of a freezer contents.
Does any university or department have enterprise installations? Which platform?
by Luka Zupancic ,
post on 13 January 2017 |
Reply
Hi Allen, thank you for your feedback!
I have to agree with you there, this was a problem I faced in all the labs I have worked at so far. Many of the above included ELNs contain some form of sample inventory (eg. Labguru, Benchling, sciNote, etc.), which can be used to monitor samples about to expire as well. For example, I currently use sciNote, which allows me to assign my samples to sample groups (eg “soon to expire”) as well as to individual projects and trace them in that way. Hope this helps!
by Roger Summers ,
post on 14 December 2016 |
Reply
All of these products still require a post process review, are clunky and cause more problem than they intend to solve. Check out Archware. This ELN comes with lanyard worn scanners to be used with a tablet device that allows you to simply scan components and instruments to auto-populate information. Plus the informationis reviewed immediately at the time of entry, avoiding errors before they can happen.
by Luka Zupančič ,
post on 14 December 2016 |
Reply
Dear Roger,
thank you for your feedback and for your suggestion. However I never came across Archware and after inspecting their web page, I noticed that they refer to the product as a quality management system and not an actual ELN. As such, I do not consider it a top contender on the list of ELNs.
by Arturo Casini ,
post on 7 December 2016 |
Reply
The post does not disclose that this blog is actually operated by the developers of SciNote, which coincidentally ranks #1 in this list. I like SciNote but I find this a bit offputting. Can you comment on this?
by Luka Zupančič ,
post on 9 December 2016 |
Reply
Dear Arturo,
Thank you for your question. As a researcher frustrated with the limitations of paper lab books, I´ve been looking for an ELN for quite some time. In the process I also tried out sciNote and even participated in it´s beta testing phase. It was the last ELN I tested and it proved to best fit my needs.
Having finally found my ideal solution, I volunteered to write a piece about my journey of finding an ELN for Splice, to show my support and to help others in the same frustrating situation I was in for so long. The article offers an overview of the ELNs I’ve tried, as well as my personal evaluation of them.
Splice is an independent blog with contributions coming mainly from independent researchers from various institutions, such as myself. I still use sciNote every day and I firmly stand by my opinion, expressed in this article.
Thanks for your review. As full disclosure, I am the co-founder and CEO of LabArchives.. While I can’t argue with your subjective criteria, there are definite factual inaccuracies in your article as it relates to our product. For example, one of the “cons” for LabArchives is that “Local installation not possible”. This is untrue: We have offered a locally installed version since 2010 and have many users of this product, including the NIH. You also suggest that “Attached PDF files lose their format” which is also untrue. All files keep their original format.
I would also question some of your grading criteria. For example, under the category of “INTEROPERABILITY AND FLEXIBILITY”, LabArchives meets all of these (we have iOS and Android Apps, are Cloud based, work on all leading OS and browsers, include real-time collaborative tools, have an extensive and robust API, and include a free tool, FolderMonitor, that allows importing of data from scientific instruments. And yet you score LabArchives just 3/5 stars.
I hope that you will take a more careful look at our product. We would be glad to arrange a demonstration so that you can better understand the functionality that you are reviewing as well many other powerful tools that it includes.
Hello Earl, thank you for the insight and your comment. It came just at the right moment, we are planning to post the updated version of the article, with more in depth information. We value your opinion and will be glad to update the information on your product. The number of ELNs available today is growing and good information is crucial. The authors of articles on Splice provide opinion from their point of view as experienced scientists and IT enthusiasts. We believe LabArchives is one of the Top ELNs available today, depending on the preferences and needs of specific labs. We are glad you reached out and provided more information and good critique. It is greatly appreciated.
by James Burchfield ,
post on 5 January 2017 |
Reply
I have used LabArchives for ~2 years now. It works, has good levels of control and oversight. To me what it lacks is project and data management integration. In the digital age the ideal would be a system that integrates all these things. It should simplify everyday life and improve workflow and data retention and transparency between lab members. IT should contain a protocol repository, the key steps of which are automatically imported into any given experiment. It should have the facillity for integrating and manging repositories/registries or reagant lists.
LabArchives is very much a blank canvas that requires the user to impose structure and order it. I would rate it 3 /5. This is with referentce to the ideal which to my knowledge does not exist. I cannot comment on any of the others as I have not used them.
Two other obvious choices you left out: RSpace ELN, which is specifically designed for integrated academic Research Data Management (RDM) workflows (try the free version at community.researchspace.com) and for high compliance labs, CERF (cerf-notebook.com) which has been in continuous use by research labs worldwide for more than a decade.
Hi Robert, thank you for your comment. I did come across RSpace and CERF, they both indeed seem like solid ELN platforms with several useful and unique features. However Rspace just barely fell short of reaching the top 7 list due to its somewhat dull and non-intuitive GUI, while CERF was not accessible online without having to write a personal email to the developers – which I find is a major disadvantage.
Hi Wouter, thank you for reaching out and for your comment. I did come across eLabjournal but was unfortunately unable to register an account with a private email address. I saw/see this as a major drawback for many researchers, who do not have an organization domain (eg. students, contractors,…) but would nevertheless like to transition to an ELN.
The system is open for anyone to trial the system, so I would be happy to offer you a free eLabJournal trial. Part of the system functionality is also to offer sharing options across labs within the institute. For the best user experience, intitute recognition is automatic based on email domain of the institute.
Did I mention that electronic lab notebooks (ELNs) are coffee-proof?
Security aspect should be a key factor when making decision concerning this kind of products, especially if you’re either doing research that has potentially commercially valuable results (your research contract may actually require you to take specific precautions) and/or your data is sensitive as defined in the legislation (think EU GDPR, that covers humane genetic data, for instance).
So true! Although the criteria used in this review to score the ELN’s are important, we (as provider of the Electronic Lab Notebook eLABJournal), are challenged by our customers every day to show that we provide a secure ELN solution. Besides supporting essential security features, such as enforcing password policies and two-step verification, ISO27001 certification of the vendor is essential to show that security is priority and that measures to safeguard the data of customers are in place. Also, offering the flexibility to choose between hosting of the software in the cloud or on own servers (yet the option to switch at any time), is important to comply with strict security policies of organizations which do not permit the use of cloud hosted solutions.
Another good one that is not as well-known yet but has many of these desired features is CERF. It comes from the same company as RSpace, is desktop-based (meaning it can be used offline), and has one of the better search engines anywhere to find information you put in years ago. If you need to be 21CRF11 compliant as well, it has got that covered. The only real disadvantage is that the GUI looks like it’s from the early 2000’s, but it is still something I wish I had in college back in 2014, espcially in chemistry class. The 3-D models of molecules are cool!
A GMP Life Science Manufacturing environment needs a 21 CFR 11 Compliant solution. FDA Regulatory GMP Pharma, BioTech & Medical Device manufacturing plants use OpsTrakker E-Logbook Solution by Enhanced Information Solutions out of Stillwater MN.
We used LabGuru, but recently moved to LabSpace.io.
I don’t know how much labs could pay for such things… So only free one 🙂
Greetings,
I am a co-founder of Docollab.
I would like to point out that Docollab is compatible with mobile devices. It has been tested with Chrome, Firefox and Opera on Android, and Safari on iOS.
I’m not sure what “Not possible to write comments” mean, but Docollab does provide a rich document editor in which you can write pretty much anything, including comments, and review past revisions of the document. Furthermore, it provides a task management feature in which you can add comments to tasks.
We would appreciate if these details could be updated. If you have any more questions, you are welcome to contact us at
Thanks,
Gabi
Hi Gabi,
thank you for your comment. It´s possible that some functionalities have been updated since I last tried out Docollab. I will definitely consider the features you mentioned for my next update of the article. Appreciate your help, will reach out if I encounter any questions in the process.
Hi Luka,
do you care to point out that you are the brother of Klemen Zupančič who is a Business Development Executive with biosistemika (https://biosistemika.com/team/), the company that offers SciNote and is magically rated first place here?
I think the conflict of interest is quite obvious here – and luckily, most researchers try out different softwares and are able to draw their own conclusions – which in many cases, result in a quite different ranking than the one postulated here.
Dear Florian,
thank you for your comment and for bringing up the question. As I pointed out several times below, the article reflects my professional opinion as a scientific researcher and is by no means a representation of a larger cohort of people or an organization for that matter. It´s an inherently personal view I firmly stand by, shaped by a great deal of effort invested in trying out numerous ELNs including your company´s ELN labfolder. If nothing else, my signature under this review should be a clear testament of my intent and good faith.
I feel it´s needles to say that different people would have scored it differently, I absolutely agree with you on that notion. I openly welcome all comments, experiences, and opinions surrounding the ELNs in question and had previously updated the scores based on constructive feedback from the comments.
I think it’s a bit surprising that the author didn’t just say “Yes he’s my brother” or “No he’s not”.
Declaring the conflict of interest doesn’t mean your opinion is invalid. A conflict of interest may be more perceived than real or may have effects on you that are not conscious. Sometimes declaring a perceived or possible conflict of interest will actually increase your credibility because readers can respect the fact that you have considered and disclosed possible sources of bias.
As scientists it is important to disclose conflicts of interest even if we genuinely believe that we are not affected by them.
Good point James!
Instead of writing two paragraphs of “needless to say” things, a simple answer “yes” or “no” would have sufficed and definitely improve the credibility of the post.
However, the signature clearly states that the blog is sponsored by biosistemika, which is a quite fair statement too.
HI Luka,
I personally have contacted each ELN venders and have them demoed to me, it took me more than two months. One of the outstanding ELN that not seeing here is the Labii ELN. You will be amazed how it different to all other existing ELNs in both design and functions and how it can link the experiments, protocols, samples, reagents, et.al all together. I specifically like it to be able to extract the metadata from lab note for statistic data analysis. You can find it at this link: https://www.labsexplorer.com/c/2017-review-of-best-electronic-laboratory-notebooks_6
Hi Young Wu, appreciate your feedback! Labii does seem like an interesting option after a quick inspection, however I would need to examine it first-hand before commenting on its functionality and usability further. For now, the information provided on the product website seems rather scarce. Nevertheless, I would happily consider reviewing Labii in a possible update to this review.
Hi Luka, Do you have a chance to review it? Our company is using Labii. It is just released a new version. I like it for the freedom to customize what data to store, what column to have and what details to insert. It also introduces the concept of widgets, which enables adding the functions to meet each lab’s requirement. My favorite part is pay-per-use. I only pay for the records I created.
It has 5th biggest ELN and LIMS market/visibility based on SEMrush, which are much higher than Benchling and Scinote.
Hi, Luka,
Thank you for the article and for reviewing Mbook (I am the CEO of Mestrelab, anyone reading my comment should be aware of that).
I wanted to comment to point out a couple of inaccuracies.
Firstly, Mbook does have a free 45 day account, for those that want to try it out. Your reason to give a significant amount of weight to price is the fact that researchers like to try before they buy. This is certainly possible with Mbook. Of course, whether a 45 day or a 10 GB trial are more extensive, depends on the number of users and on the amount of data that is stored in the ELN.
Secondly, Mbook has indeed an in-house installation, as highlighted on our website. It is designed as a Cloud Solution, but we make available an installer for in-house installation to any institutions not happy putting their data on the cloud.
Finally, intuitiveness of interface is a subjective matter, and therefore I cannot really comment on your evaluation there. Mbook is designed for synthetic chemistry, and it makes sense to evaluate it from that viewpoint. It is aiming at making the creation of reactions, stoichiometry tables, experimental protocols and the attachment of analytical and other data to experiments as simple as possible. Of course, that may not work so well for other workflows or use cases, which it is not targeted to doing. From a synthetic chemist perspective, I would expect that structure editor, structure search, integrated inventory, self populating stoichiometry tables and immediate access to all analytical data are all points to value, which do not seem to be considered on your review, so this might be a point worth making.
Best Regards
Santi
Hi Santi,
thank you for your feedback, I appreciate you taking the time. Allow me to comment on the points you highlighted.
1) The »Free version« score refers to weather a free version of the software exists, which can be used continuously and not merely tried out. I do not see a 45-day account option as a free version but rather as a trial, which is also how it is advertised on your web page. However, I did appreciate the trial version and did award Mbook a respectable 4/5 points in the »Business model and Pricing« category.
2) I now understand you offer an in-house installation and I appreciate you bringing that up for the readers. This seems to be an honest mistake on my part, however I do recall that feature was not communicated very clearly at the time of my testing. I would be happy to take it into account in the upcoming update of this review.
3) You put it well and there is not much left to be said. The UX is in its nature a subjective matter and I´m positive people with different backgrounds would score differently. However, I did focus on aspects that make an ELN user friendly to a broader range of users (i.e. researchers), and not a very specific segment. I am not a synthetic chemist and did find myself frequently stumbling over hurdles in design that unfortunately diminished my experience with Mbook.
I would like to state that Mbook did prove as a valid candidate and I definitely see it as a solid ELN. That´s why I included it on the »Top 9« list, among many others that did not do the job as good.
Just a small remark: Is a bit strange that the first place goes to the company that powered this list: Biosistemika LLC
Hi Paul, thank you for your comment, this has already been discussed bellow. Posting my reply again for your convenience:
“As a researcher frustrated with the limitations of paper lab books, I´ve been looking for an ELN for quite some time. In the process I also tried out sciNote and even participated in it´s beta testing phase. It was the last ELN I tested and it proved to best fit my needs.
Having finally found my ideal solution, I volunteered to write a piece about my journey of finding an ELN for Splice, to show my support and to help others in the same frustrating situation I was in for so long. The article offers an overview of the ELNs I’ve tried, as well as my personal evaluation of them.
Splice is an independent blog with contributions coming mainly from independent researchers from various institutions, such as myself. I still use sciNote every day and I firmly stand by my opinion, expressed in this article.”
Hi,
Although your justification is reasonable, there is a lack of unbias analysis. For example:
In INTEROPERABILITY AND FLEXIBILITY section you mentioned 5 bullet points:
Multi device compatibility
Working with different operating systems and browsers
Cloud
Real-time collaboration
Instrument integration and open APIs
I personally tested LabArchives and Labfolder and both meet all the requirements, but end just with 3 out of 5.
Curiously, scinote does not offer an API (according to their own FAQ) and lacks dedicated mobile apps (there is just a shortcut option as they mention here https://scinote.net/product/mobile/) but they still had a better evaluation in that category 🙂
Hi Mark, thanks for your input!
You bring up a valid point there and I do agree with you, everybody is entitled to their own opinion and many people would have surely scored the ELNs differently, based on their own needs and experiences.
In terms of interoperability, mine were not the best with LabArchives and Labfolder at the time of testing. Please note that this article is a second revision of the original one, and it could very well be that both products experienced updates in that area since then. However, if you scroll down you will find other people reported interoperability issues with the ELNs in question as well.
You are spot on regarding sciNote, those limitations are on point and did land them a lower score. Since their mobile version actually worked great for me and still does, I only deducted one point for the lack of an API.
I am surprised to not see the Findings app amongst these! I have just tried sciNote and I would say that the user experience of Findings the the functionality it offers are far superior. You would need to pay for a license, but I definitely think it’s more than worth it!
Hi Stelios, appreciate your feedback! Findings ELN does seem like an interesting pick after a quick inspection, however I do realize it is only available for iOS systems. I run all experiments in a PC setting and generally find solutions that are limited to a single platform disadvantaged. If a PC version comes out any time soon and an update to this review ever occurs, I would be happy to give Findings a try.
FINDING AN ELN (DUMPING SCINOTE)
Thanks for putting a list of these together, this seems to be the only place on the www that has some comprehensive review of ELNs. I run a research core and we do several projects for multiple labs and we really need an ELN. I am just testing a few, and hopefully will find time to write more about my impressions and final choice.
I wanted to comment about the ratings in this review: I believe that pricing is largely over-emphasized here, a product that takes more work to create will obviously create more costs and be more expensive. User experience also seems to lean towards simple programs, it seems that more complex ELNs with more modules are rated poorly just because it took the reviewers more time to understand the different parts. If an ELN will be used for standard operations am am willing to pay for it and spend some time to learn how to use it.
I believe that is what put the rather bare-bones ELN “SCINOTE” on top of the list. SCINOTE is the first one I dis-regarded, yes their licensing is free for most and sharing is somewhat easy, but recording procedures is frankly a pain. There is no way to add tables and calculation formulas, no annotation of result files, no sketching and no repository to organize reagents that are created.
Hi Christoph, thank you for your input! You bring up a good point, not all of the ELNs and their features in this review are equally important for everyone. Obviously expectations from lab to lab and researcher to researcher will differ and you highlighted some very good examples of that.
I tested the ELNs based on personal requirements, which I believe resemble those of a “typical researcher”. I needed a solid and reliable ELN solution to solve my everyday issues with experimental design and laboratory data management for a reasonable budget. I defined the scoring criteria to best represent those needs, which I believe correlate to a much larger portion of researchers out there. However, I absolutely agree with you, if the criteria were set in a different manner, the outcome would undoubtedly differ accordingly.
Great review. Rspace looks well adapted to academic labs from my cursory review. Glad to hear others work as well.
As someone who works across campus, and bridging researchers and facility managers I see the frustration of overfilled freezers and abandoned freezer contents when scientists retire. Facilities and office of research might support the costs of enterprise installations if ELN and sample management databases include expiration date defaults (that may be updated). This would enhance discarding of expired, forgotten or spoiled samples, which may comprise 30% or more of a freezer contents.
Does any university or department have enterprise installations? Which platform?
Hi Allen, thank you for your feedback!
I have to agree with you there, this was a problem I faced in all the labs I have worked at so far. Many of the above included ELNs contain some form of sample inventory (eg. Labguru, Benchling, sciNote, etc.), which can be used to monitor samples about to expire as well. For example, I currently use sciNote, which allows me to assign my samples to sample groups (eg “soon to expire”) as well as to individual projects and trace them in that way. Hope this helps!
All of these products still require a post process review, are clunky and cause more problem than they intend to solve. Check out Archware. This ELN comes with lanyard worn scanners to be used with a tablet device that allows you to simply scan components and instruments to auto-populate information. Plus the informationis reviewed immediately at the time of entry, avoiding errors before they can happen.
Dear Roger,
thank you for your feedback and for your suggestion. However I never came across Archware and after inspecting their web page, I noticed that they refer to the product as a quality management system and not an actual ELN. As such, I do not consider it a top contender on the list of ELNs.
The post does not disclose that this blog is actually operated by the developers of SciNote, which coincidentally ranks #1 in this list. I like SciNote but I find this a bit offputting. Can you comment on this?
Dear Arturo,
Thank you for your question. As a researcher frustrated with the limitations of paper lab books, I´ve been looking for an ELN for quite some time. In the process I also tried out sciNote and even participated in it´s beta testing phase. It was the last ELN I tested and it proved to best fit my needs.
Having finally found my ideal solution, I volunteered to write a piece about my journey of finding an ELN for Splice, to show my support and to help others in the same frustrating situation I was in for so long. The article offers an overview of the ELNs I’ve tried, as well as my personal evaluation of them.
Splice is an independent blog with contributions coming mainly from independent researchers from various institutions, such as myself. I still use sciNote every day and I firmly stand by my opinion, expressed in this article.
Another great ELN solution to consider – BookitLab ELN
Simple and intuitive, perfect for start ups and bio incubators.
Hello,
Please consider also eLabFTW, a free and open source ELN.
Thanks for your review. As full disclosure, I am the co-founder and CEO of LabArchives.. While I can’t argue with your subjective criteria, there are definite factual inaccuracies in your article as it relates to our product. For example, one of the “cons” for LabArchives is that “Local installation not possible”. This is untrue: We have offered a locally installed version since 2010 and have many users of this product, including the NIH. You also suggest that “Attached PDF files lose their format” which is also untrue. All files keep their original format.
I would also question some of your grading criteria. For example, under the category of “INTEROPERABILITY AND FLEXIBILITY”, LabArchives meets all of these (we have iOS and Android Apps, are Cloud based, work on all leading OS and browsers, include real-time collaborative tools, have an extensive and robust API, and include a free tool, FolderMonitor, that allows importing of data from scientific instruments. And yet you score LabArchives just 3/5 stars.
I hope that you will take a more careful look at our product. We would be glad to arrange a demonstration so that you can better understand the functionality that you are reviewing as well many other powerful tools that it includes.
Hello Earl, thank you for the insight and your comment. It came just at the right moment, we are planning to post the updated version of the article, with more in depth information. We value your opinion and will be glad to update the information on your product. The number of ELNs available today is growing and good information is crucial. The authors of articles on Splice provide opinion from their point of view as experienced scientists and IT enthusiasts. We believe LabArchives is one of the Top ELNs available today, depending on the preferences and needs of specific labs. We are glad you reached out and provided more information and good critique. It is greatly appreciated.
I have used LabArchives for ~2 years now. It works, has good levels of control and oversight. To me what it lacks is project and data management integration. In the digital age the ideal would be a system that integrates all these things. It should simplify everyday life and improve workflow and data retention and transparency between lab members. IT should contain a protocol repository, the key steps of which are automatically imported into any given experiment. It should have the facillity for integrating and manging repositories/registries or reagant lists.
LabArchives is very much a blank canvas that requires the user to impose structure and order it. I would rate it 3 /5. This is with referentce to the ideal which to my knowledge does not exist. I cannot comment on any of the others as I have not used them.
Two other obvious choices you left out: RSpace ELN, which is specifically designed for integrated academic Research Data Management (RDM) workflows (try the free version at community.researchspace.com) and for high compliance labs, CERF (cerf-notebook.com) which has been in continuous use by research labs worldwide for more than a decade.
Hi Robert, thank you for your comment. I did come across RSpace and CERF, they both indeed seem like solid ELN platforms with several useful and unique features. However Rspace just barely fell short of reaching the top 7 list due to its somewhat dull and non-intuitive GUI, while CERF was not accessible online without having to write a personal email to the developers – which I find is a major disadvantage.
Good review! Seems that you missed out reviewing some other great solutions however, such as the Electronic Lab Notebook eLabJournal.
Hi Wouter, thank you for reaching out and for your comment. I did come across eLabjournal but was unfortunately unable to register an account with a private email address. I saw/see this as a major drawback for many researchers, who do not have an organization domain (eg. students, contractors,…) but would nevertheless like to transition to an ELN.
The system is open for anyone to trial the system, so I would be happy to offer you a free eLabJournal trial. Part of the system functionality is also to offer sharing options across labs within the institute. For the best user experience, intitute recognition is automatic based on email domain of the institute.
This is very interesting, Would I be able to speak to get in touch with a consultant in Melbourne, Australia?
Regards, Helen