So, why do you even need an electronic lab notebook at all?
A notebook, pen, and neat handwriting are still the basics for some scientists.
But in reality, paper lab journals are losing ground. The cost of loss is too great: 17% of research data disappears simply because it stayed on the pages and didn’t make it into the digital space.
In an era where data must be interoperable, transferable, and encrypted, ELN is becoming the standard and not only in pharma or biotech. It is now a must-have for universities, startups, and private labs as well.
What did we Evaluate When Selecting the best ELNs?
To avoid drowning in a list of hundreds of systems, we focused on three key blocks:
- Usability (from interface to mobile version);
- Flexibility and integration (working in the cloud, API support, security);
- Pricing policy (availability of free versions, transparency of licenses).
Let’s get started.
SciNote
If fast implementation, a clear interface, and a clear structure are important to you, SciNote is a great choice. It’s designed by biologists for biologists and offers not just an electronic notebook but a complete platform with protocols, templates, inventory management, and reports. It’s a great option for academic teams and startups.
RSpace
A serious academic tool with a long history. Unlike its more “boxed” competitors, RSpace emphasizes flexibility and interoperability. It can integrate with eCAT, supports chemical structures, and offers advanced analytics. The interface could do with an update, but it is compensated for by its extensive features.
Benchling
A real giant in the ELN world, especially in the biotech industry. Equipped with advanced DNA tools, including CRISPR and primers. Offers a free version for academic users, but many features are oriented towards the corporate market. Newcomers may find it overwhelming.
Sapio Sciences
This isn’t just an ELN it’s an entire lab platform with LIMS integration and a data visualization module. There’s even a “lab AI” named Jarvis that helps collect and organize data in real time. Alas, there is no free version, and mastering it will take time.
eLabJournal
Developed as part of the eLabNext product family, and works well in an ecosystem with eLabInventory and eLabProtocols. It is flexible with protocols, offers collaboration features, and has good integration tools. The interface is a bit outdated, and there is no full free version yet.
Labguru
An all-in-one platform combining ELN, inventory management, automation and analytics. Interested primarily in biomedical labs that need a complete ecosystem. The interface is modern, but mastering it requires patience. No free plan either, subscription is not cheap.
Labfolder
A solution from the German team Labforward. Suitable for small teams:
up to three users for free. Built-in sketching support, mobile app, and Mendeley integration make it a good choice for young teams. However, the design and UX clearly need an update.
eLabFTW
A rare representative of an open-source ELN. You can install locally, customize, and control at all levels. Suitable for advanced techies and organizations that value independence and privacy. A simple interface and minimal documentation are not for beginners.
LabArchives
Academic classic. Easy to install, can work with PubMed and GraphPad Prism, popular in US universities. The functionality is quite sufficient, but the visual part is in need of an upgrade. Free storage is limited to only 1 GB.
What’s Next?
None of the ELNs is perfect. But each can be exactly the tool you need, especially if you know what you want: flexibility? Accountability? Simplicity? Or all of the above?
If you’re on the cusp of moving from paper to digital, take our list as a map, not a final verdict. ELN isn’t just software. It’s an infrastructure for future discovery.
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